Version 5.4
Mus musculus Protein: Lect2
Summary
InnateDB Protein IDBP-157370.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lect2
Protein Name leukocyte cell-derived chemotaxin 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000060495
InnateDB Gene IDBG-157368 (Lect2)
Protein Structure
UniProt Annotation
Function Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Highly expressed in liver and weakly in testis. Not expressed in heart, brain, spleen, lung, skeletal muscle and kidney.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0042802 identical protein binding
Biological Process
GO:0006935 chemotaxis
GO:0030178 negative regulation of Wnt signaling pathway
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:1278342
InterPro IPR016047 Peptidase M23
IPR017381 Leukocyte cell-derived chemotaxin 2, chordata
PFAM PF01551
PRINTS
PIRSF PIRSF038085
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O88803
PhosphoSite PhosphoSite-O88803
TrEMBL
UniProt Splice Variant
Entrez Gene 16841
UniGene Mm.16973
RefSeq NP_034832
MGI ID
MGI Symbol Lect2
OMIM
CCDS CCDS26564
HPRD
IMGT
EMBL AB009687 AB009688 AB009689 AF035161 AK131971 BC027753 CH466546
GenPept AAF13302 AAH27753 BAA33383 BAA33384 BAA33385 BAA33386 BAE20911 EDL41242

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca