Version 5.4
Homo sapiens Protein: APH1B
Summary
InnateDB Protein IDBP-15760.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APH1B
Protein Name anterior pharynx defective 1 homolog B (C. elegans)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000369697
InnateDB Gene IDBG-15754 (APH1B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0016485 protein processing
GO:0043085 positive regulation of catalytic activity
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR009294 Gamma-secretase subunit Aph-1
PFAM PF06105
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q4R1J8
UniProt Splice Variant
Entrez Gene 83464
UniGene Hs.668607
RefSeq
HUGO HGNC:24080
OMIM 607630
CCDS
HPRD 06361
IMGT
EMBL AB197122 AC016207
GenPept BAE02660

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca