Version 5.4
Mus musculus Protein: Tmem237
Summary
InnateDB Protein IDBP-157803.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmem237
Protein Name amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000084745
InnateDB Gene IDBG-157797 (Tmem237)
Protein Structure
UniProt Annotation
Function Component of the transition zone in primary cilia. Required for ciliogenesis. {ECO:0000269PubMed:22152675}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell projection, cilium {ECO:0000269PubMed:22152675}. Note=Localizes at the proximal region of primary cilia were observed, consistent with localization to the transition zone.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0030111 regulation of Wnt signaling pathway
GO:0042384 cilium assembly
Cellular Component
GO:0016021 integral component of membrane
GO:0035869 ciliary transition zone
Protein Structure and Domains
PDB ID MGI:2138365
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3V0J1
PhosphoSite PhosphoSite-Q3V0J1
TrEMBL
UniProt Splice Variant
Entrez Gene 381259
UniGene Mm.415906
RefSeq NP_001032901
MGI ID
MGI Symbol Tmem237
OMIM
CCDS CCDS14984
HPRD
IMGT
EMBL AC133162 AK133112 AK167733 BC147243 BC147244
GenPept AAI47244 AAI47245 BAE21513 BAE39774

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca