InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tcf7l1

Summary

InnateDB Protein

IDBP-157942.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tcf7l1

Protein Name

transcription factor 7-like 1 (T-cell specific, HMG box)

Synonyms

bHLHb21; Tcf-3; Tcf3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000069403

InnateDB Gene

IDBG-157940 (Tcf7l1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008013	beta-catenin binding
GO:0043565	sequence-specific DNA binding
GO:0044212	transcription regulatory region DNA binding

Biological Process

GO:0007420	brain development
GO:0008595	anterior/posterior axis specification, embryo
GO:0035019	somatic stem cell maintenance
GO:0043588	skin development
GO:0045892	negative regulation of transcription, DNA-templated
GO:0046022	positive regulation of transcription from RNA polymerase II promoter during mitosis
GO:0048319	axial mesoderm morphogenesis
GO:0048699	generation of neurons
GO:0048863	stem cell differentiation
GO:0060070	canonical Wnt signaling pathway
GO:2000036	regulation of stem cell maintenance