Mus musculus Protein: Mpp4 | |||||||
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Summary | |||||||
InnateDB Protein | IDBP-157989.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Mpp4 | ||||||
Protein Name | membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) | ||||||
Synonyms | |||||||
Species | Mus musculus | ||||||
Ensembl Protein | ENSMUSP00000077914 | ||||||
InnateDB Gene | IDBG-252103 (Mpp4) | ||||||
Protein Structure | |||||||
UniProt Annotation | |||||||
Function | May play a role in retinal photoreceptors development. {ECO:0000269PubMed:12859944}. | ||||||
Subcellular Localization | Cytoplasm {ECO:0000269PubMed:12859944, ECO:0000269PubMed:15558731}. Note=Localized at photoreceptor synaptic terminals in retina. Localized in rod and cone photoreceptors at the plasma membrane and at membranes of intracellular vesicles around the subapical region (SAR) and adherens junction, and in the outer plexiform layer (OPL). | ||||||
Disease Associations | |||||||
Tissue Specificity | Detected in the retina (at protein level). Highly enriched in the retina where it is mainly expressed by rod photoreceptors; detected in the inner segment of the photoreceptor layer and in the outer nuclear layer. Also detected at much lower levels in pineal gland, cerebellum, cortex, hippocampus, olfactory bulb, heart, liver and spleen. Expressed in the CA1-CA3 regions of pyramidal cell layers and in the granule cell layer of dentate gyrus in the hippocampus. In the cerebellum, expressed in Purkinje cells and throughout the granule cell layer. In the olfactory bulb, expressed in mitral cells. {ECO:0000269PubMed:12127943, ECO:0000269PubMed:12384283, ECO:0000269PubMed:12859944, ECO:0000269PubMed:15558731}. | ||||||
Comments | |||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||
PDB ID | MGI:2386681 | ||||||
InterPro |
IPR001452
SH3 domain IPR001478 PDZ domain IPR004172 L27 IPR008144 Guanylate kinase-like IPR008145 Guanylate kinase/L-type calcium channel beta subunit IPR011511 Variant SH3 domain IPR014775 L27, C-terminal IPR027417 P-loop containing nucleoside triphosphate hydrolase |
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PFAM |
PF00018
PF14604 PF00595 PF13180 PF00625 PF07653 PF02828 |
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PRINTS |
PR00452
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PIRSF | |||||||
SMART |
SM00326
SM00228 SM00569 SM00072 |
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TIGRFAMs | |||||||
Post-translational Modifications | |||||||
Modification | |||||||
Cross-References | |||||||
SwissProt | Q6P7F1 | ||||||
PhosphoSite | PhosphoSite-Q6P7F1 | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 227157 | ||||||
UniGene | Mm.408609 | ||||||
RefSeq | NP_660125 | ||||||
MGI ID | |||||||
MGI Symbol | Mpp4 | ||||||
OMIM | |||||||
CCDS | CCDS48271 | ||||||
HPRD | |||||||
IMGT | |||||||
EMBL | AB059357 AB059358 AJ748820 AK044682 AK088771 BC061694 BC116723 | ||||||
GenPept | AAH61694 AAI16724 BAB69494 BAB69495 BAC32031 BAC40562 CAG38657 | ||||||