Mus musculus Protein: Eif2b2
Summary
InnateDB Protein IDBP-158159.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif2b2
Protein Name eukaryotic translation initiation factor 2B, subunit 2 beta
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000004910
InnateDB Gene IDBG-158157 (Eif2b2)
Protein Structure
UniProt Annotation
Function Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003743 translation initiation factor activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005525 GTP binding
Biological Process
GO:0001541 ovarian follicle development
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
GO:0007417 central nervous system development
GO:0014003 oligodendrocyte development
GO:0042552 myelination
GO:0043087 regulation of GTPase activity
GO:0043547 positive regulation of GTPase activity
GO:0044237 cellular metabolic process
GO:0051716 cellular response to stimulus
Cellular Component
GO:0005737 cytoplasm
GO:0005851 eukaryotic translation initiation factor 2B complex
Protein Structure and Domains
PDB ID MGI:2145118
InterPro IPR000649 Initiation factor 2B-related
PFAM PF01008
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99LD9
PhosphoSite PhosphoSite-Q99LD9
TrEMBL
UniProt Splice Variant
Entrez Gene 217715
UniGene Mm.29041
RefSeq NP_663420
MGI ID
MGI Symbol Eif2b2
OMIM
CCDS CCDS26053
HPRD
IMGT
EMBL AK049731 BC003326
GenPept AAH03326 BAC33897