InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rasef

Summary

InnateDB Protein

IDBP-158188.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rasef

Protein Name

RAS and EF hand domain containing

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000099901

InnateDB Gene

IDBG-158184 (Rasef)

Protein Structure

UniProt Annotation

Function

Binds predominantly GDP, and also GTP. {ECO:0000250}.

Subcellular Localization

Cytoplasm, perinuclear region {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005525	GTP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0006886	intracellular protein transport
GO:0006913	nucleocytoplasmic transport
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport

Cellular Component

GO:0005575	cellular_component
GO:0005622	intracellular
GO:0016020	membrane
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

MGI:2448565

InterPro

IPR001806 Small GTPase superfamily
IPR002041 Ran GTPase
IPR003578 Small GTPase superfamily, Rho type
IPR003579 Small GTPase superfamily, Rab type
IPR005225 Small GTP-binding protein domain
IPR006689 Small GTPase superfamily, ARF/SAR type
IPR013684 Mitochondrial Rho-like
IPR020849 Small GTPase superfamily, Ras type
IPR024156 Small GTPase superfamily, ARF type
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00071
PF00025
PF08477

PRINTS

PR00449
PR00627
PR00328

PIRSF

SMART

SM00176
SM00174
SM00175
SM00173
SM00177

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt