Version 5.4
Mus musculus Protein: Cstf2t
Summary
InnateDB Protein IDBP-158339.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cstf2t
Protein Name cleavage stimulation factor, 3' pre-RNA subunit 2, tau
Synonyms 64kDa; C77975; tauCstF-64; tCstF-64;
Species Mus musculus
Ensembl Protein ENSMUSP00000093831
InnateDB Gene IDBG-158337 (Cstf2t)
Protein Structure
UniProt Annotation
Function May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Directly involved in the binding to pre-mRNAs. {ECO:0000269PubMed:11113135}.
Subcellular Localization Nucleus {ECO:0000269PubMed:14681198}.
Disease Associations
Tissue Specificity Expressed in testes, where it is restricted to pachytene spermatocytes and spermatids, and in the brain (at protein level). {ECO:0000269PubMed:14681198}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006378 mRNA polyadenylation
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1932622
InterPro IPR000504 RNA recognition motif domain
PFAM PF00076
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C7E9
PhosphoSite PhosphoSite-Q8C7E9
TrEMBL
UniProt Splice Variant
Entrez Gene 83410
UniGene Mm.490369
RefSeq NP_112539
MGI ID
MGI Symbol Cstf2t
OMIM
CCDS CCDS37958
HPRD
IMGT
EMBL AF322194 AK034853 AK050407 AK082910 AK084696 AK173002 BC026995
GenPept AAG40327 AAH26995 BAC28855 BAC34240 BAC38683 BAC39256 BAD32280

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca