InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Frmd3

Summary

InnateDB Protein

IDBP-158387.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Frmd3

Protein Name

FERM domain containing 3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000095615

InnateDB Gene

IDBG-158385 (Frmd3)

Protein Structure

UniProt Annotation

Function

Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer. {ECO:0000250}.

Subcellular Localization

Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0008092	cytoskeletal protein binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005575	cellular_component
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0016021	integral component of membrane
GO:0019898	extrinsic component of membrane

Protein Structure and Domains

PDB ID

MGI:2442466

InterPro

IPR000299 FERM domain
IPR000798 Ezrin/radixin/moesin like
IPR014847 FERM adjacent (FA)
IPR018979 FERM, N-terminal
IPR018980 FERM, C-terminal PH-like domain
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR019750 Band 4.1 family
IPR029071 Ubiquitin-related domain

PFAM

PF08736
PF09379
PF09380
PF00373

PRINTS

PR00661
PR00935

PIRSF

SMART

SM00295

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt