Version 5.4
Mus musculus Protein: Tox4
Summary
InnateDB Protein IDBP-158590.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tox4
Protein Name TOX high mobility group box family member 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000022766
InnateDB Gene IDBG-158588 (Tox4)
Protein Structure
UniProt Annotation
Function Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00267}. Note=Associated with chromatin.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
GO:0072357 PTW/PP1 phosphatase complex
Protein Structure and Domains
PDB ID MGI:1915389
InterPro IPR009071 High mobility group box domain
PFAM PF00505
PF09011
PRINTS
PIRSF
SMART SM00398
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BU11
PhosphoSite PhosphoSite-Q8BU11
TrEMBL Q6A006
UniProt Splice Variant
Entrez Gene 268741
UniGene Mm.474864
RefSeq NP_075923
MGI ID
MGI Symbol Tox4
OMIM
CCDS CCDS36920
HPRD
IMGT
EMBL AF228408 AK019980 AK088144 AK137050 AK147023 AK147834 AK173012 BC050091
GenPept AAH50091 AAK00713 BAB31949 BAC40170 BAD32290 BAE23218 BAE27616 BAE28170

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca