InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Jakmip1

Summary

InnateDB Protein

IDBP-158687.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Jakmip1

Protein Name

janus kinase and microtubule interacting protein 1

Synonyms

5830437M04Rik; C330021K24Rik; Gababrbp; Marlin-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000038504

InnateDB Gene

IDBG-158685 (Jakmip1)

Protein Structure

UniProt Annotation

Function

Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. {ECO:0000269PubMed:17532644}.

Subcellular Localization

Cytoplasm, cytoskeleton {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0008017	microtubule binding
GO:0019894	kinesin binding
GO:0019900	kinase binding
GO:0050811	GABA receptor binding

Biological Process

GO:0015031	protein transport
GO:0050890	cognition

Cellular Component

GO:0005737	cytoplasm
GO:0005874	microtubule
GO:0015630	microtubule cytoskeleton
GO:0019898	extrinsic component of membrane
GO:0030529	ribonucleoprotein complex