Version 5.4
Mus musculus Protein: Nup214
Summary
InnateDB Protein IDBP-158702.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nup214
Protein Name nucleoporin 214
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000066492
InnateDB Gene IDBG-158700 (Nup214)
Protein Structure
UniProt Annotation
Function May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex. {ECO:0000250}.
Subcellular Localization Nucleus, nuclear pore complex {ECO:0000250}. Note=Cytoplasmic filaments. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 41 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005487 nucleocytoplasmic transporter activity
GO:0005515 protein binding
Biological Process
GO:0006406 mRNA export from nucleus
GO:0006606 protein import into nucleus
GO:0006611 protein export from nucleus
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005925 focal adhesion
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID MGI:1095411
InterPro IPR001680 WD40 repeat
PFAM PF00400
PRINTS
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80U93
PhosphoSite PhosphoSite-Q80U93
TrEMBL Q8CHS9
UniProt Splice Variant
Entrez Gene 227720
UniGene Mm.289686
RefSeq NP_758472
MGI ID
MGI Symbol Nup214
OMIM
CCDS CCDS38098
HPRD
IMGT
EMBL AK122189 AK150915 AL928893 BC039282
GenPept AAH39282 BAC65471 BAE29953 CAM26045

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca