InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Polq

Summary

InnateDB Protein

IDBP-158805.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Polq

Protein Name

polymerase (DNA directed), theta

Synonyms

A430110D14Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000059757

InnateDB Gene

IDBG-158803 (Polq)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003887	DNA-directed DNA polymerase activity
GO:0004386	helicase activity
GO:0005524	ATP binding
GO:0043142	single-stranded DNA-dependent ATPase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0006260	DNA replication
GO:0006261	DNA-dependent DNA replication
GO:0006281	DNA repair

Cellular Component

Protein Structure and Domains

PDB ID

MGI:2155399

InterPro

IPR001098 DNA-directed DNA polymerase, family A, palm domain
IPR001650 Helicase, C-terminal
IPR002298 DNA polymerase A
IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
IPR012337 Ribonuclease H-like domain
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00476
PF00271
PF00270

PRINTS

PR00868

PIRSF

SMART

SM00482
SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt