Version 5.4
Mus musculus Protein: Sema4f
Summary
InnateDB Protein IDBP-159153.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sema4f
Protein Name sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000000641
InnateDB Gene IDBG-159151 (Sema4f)
Protein Structure
UniProt Annotation
Function Has growth cone collapse activity against retinal ganglion-cell axons. {ECO:0000250}.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
GO:0007411 axon guidance
GO:0030517 negative regulation of axon extension
GO:0031290 retinal ganglion cell axon guidance
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0045202 synapse
GO:0045211 postsynaptic membrane
Protein Structure and Domains
PDB ID MGI:1340055
InterPro IPR001627 Sema domain
IPR002165 Plexin
IPR016201 Plexin-like fold
PFAM PF01403
PF01437
PRINTS
PIRSF
SMART SM00630
SM00423
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Z123
PhosphoSite PhosphoSite-Q9Z123
TrEMBL Q810B2
UniProt Splice Variant
Entrez Gene 20355
UniGene Mm.270543
RefSeq NP_035480
MGI ID
MGI Symbol Sema4f
OMIM
CCDS CCDS20264
HPRD
IMGT
EMBL AB021291 AB022316 AC158652 AF038652 BC094567 CH466523
GenPept AAD02103 AAH94567 BAA75630 BAA75634 EDK99043

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca