Version 5.4
Mus musculus Protein: Nlrp4a
Summary
InnateDB Protein IDBP-159231.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nlrp4a
Protein Name NLR family, pyrin domain containing 4A
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000066841
InnateDB Gene IDBG-159229 (Nlrp4a)
Protein Structure
UniProt Annotation
Function May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005524 ATP binding
Biological Process
GO:0006952 defense response
GO:0006954 inflammatory response
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:2443697
InterPro IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype
IPR004020 DAPIN domain
IPR007111 NACHT nucleoside triphosphatase
IPR011029 Death-like domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF02758
PRINTS
PIRSF
SMART SM00368
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BU40
PhosphoSite PhosphoSite-Q8BU40
TrEMBL Q3TSD5
UniProt Splice Variant
Entrez Gene 243880
UniGene Mm.322356
RefSeq NP_766484
MGI ID
MGI Symbol Nlrp4a
OMIM
CCDS CCDS21003
HPRD
IMGT
EMBL AK087843 AK162125 AY355341 AY596200 BC141342 BC141343 CH466593
GenPept AAI41343 AAI41344 AAR14738 AAU06321 BAC40024 BAE36740 EDL24221

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca