Version 5.4
Mus musculus Protein: Lipn
Summary
InnateDB Protein IDBP-159264.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lipn
Protein Name lipase, family member N
Synonyms 2210418G03Rik; Lipl4;
Species Mus musculus
Ensembl Protein ENSMUSP00000025682
InnateDB Gene IDBG-159262 (Lipn)
Protein Structure
UniProt Annotation
Function Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016788 hydrolase activity, acting on ester bonds
Biological Process
GO:0006629 lipid metabolic process
GO:0008150 biological_process
GO:0016042 lipid catabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:1917416
InterPro IPR000073 Alpha/beta hydrolase fold-1
IPR006693 Partial AB-hydrolase lipase domain
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00561
PF04083
PRINTS PR00111
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3U4B4
PhosphoSite PhosphoSite-
TrEMBL D3YVB0
UniProt Splice Variant
Entrez Gene 70166
UniGene Mm.75602
RefSeq NP_081616
MGI ID
MGI Symbol Lipn
OMIM
CCDS CCDS37962
HPRD
IMGT
EMBL AC102119 AC165239 AK154333
GenPept BAE32519

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca