InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lipm

Summary

InnateDB Protein

IDBP-159316.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lipm

Protein Name

lipase, family member M

Synonyms

4632427C23Rik; AW227514; Lipl3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025685

InnateDB Gene

IDBG-159314 (Lipm)

Protein Structure

UniProt Annotation

Function

Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0016788	hydrolase activity, acting on ester bonds

Biological Process

GO:0006629	lipid metabolic process
GO:0008150	biological_process
GO:0016042	lipid catabolic process

Cellular Component

GO:0005575	cellular_component
GO:0005576	extracellular region

Protein Structure and Domains

PDB ID

MGI:1926003

InterPro

IPR000073 Alpha/beta hydrolase fold-1
IPR006693 Partial AB-hydrolase lipase domain
IPR029058 Alpha/Beta hydrolase fold

PFAM

PF00561
PF04083

PRINTS

PR00111

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8K2A6

PhosphoSite

PhosphoSite-Q8K2A6

TrEMBL

UniProt Splice Variant

Entrez Gene

78753

UniGene

Mm.195937

RefSeq

NP_076392

MGI ID

MGI Symbol

Lipm

OMIM

CCDS

CCDS50419

HPRD

IMGT

EMBL

AK037091 AK037214 AK085719 BC031933

GenPept

AAH31933 BAC29699 BAC29757 BAC39517