Version 5.4
Mus musculus Protein: Irf2bpl
Summary
InnateDB Protein IDBP-159519.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Irf2bpl
Protein Name RIKEN cDNA 6430527G18 gene
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000041070
InnateDB Gene IDBG-159517 (Irf2bpl)
Protein Structure
UniProt Annotation
Function May contribute to the control of female reproductive function. May play a role in gene transcription by transactivating GNRH1 promoter and repressing PENK promoter (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046543 development of secondary female sexual characteristics
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:2442463
InterPro IPR022750 Interferon regulatory factor 2-binding protein 1 & 2, zinc finger
PFAM PF11261
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K3X4
PhosphoSite PhosphoSite-Q8K3X4
TrEMBL
UniProt Splice Variant
Entrez Gene 238330
UniGene Mm.406727
RefSeq NP_665835
MGI ID
MGI Symbol Irf2bpl
OMIM
CCDS CCDS26068
HPRD
IMGT
EMBL AF525300 AK032366 AK032622 AK082791 AK140441 AK154383 AK155373 AK171043 AK173282 BC057128 BC063253
GenPept AAH57128 AAH63253 AAM82165 BAC27837 BAC27955 BAC38621 BAD32560 BAE24388 BAE32550 BAE33226 BAE42208

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca