Version 5.4
Mus musculus Protein: Zdhhc22
Summary
InnateDB Protein IDBP-159607.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zdhhc22
Protein Name zinc finger, DHHC-type containing 22
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000093177
InnateDB Gene IDBG-159589 (Zdhhc22)
Protein Structure
UniProt Annotation
Function Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008270 zinc ion binding
GO:0019706 protein-cysteine S-palmitoyltransferase activity
Biological Process
GO:0018345 protein palmitoylation
GO:0072659 protein localization to plasma membrane
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2685108
InterPro IPR000731 Sterol-sensing domain
IPR001594 Zinc finger, DHHC-type, palmitoyltransferase
PFAM PF01529
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A0PK84
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 238331
UniGene Mm.185890
RefSeq NP_001074412
MGI ID
MGI Symbol Zdhhc22
OMIM
CCDS CCDS36500
HPRD
IMGT
EMBL BC128021
GenPept AAI28022

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca