InnateDB Protein
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IDBP-159628.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Apoa1bp
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Protein Name
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apolipoprotein A-I binding protein
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000029708
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InnateDB Gene
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IDBG-159626 (Apoa1bp)
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Protein Structure
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Function |
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. {ECO:0000255HAMAP-Rule:MF_03159, ECO:0000269PubMed:21994945}.
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Subcellular Localization |
Mitochondrion {ECO:0000255HAMAP- Rule:MF_03159}. Secreted {ECO:0000255HAMAP-Rule:MF_03159, ECO:0000269PubMed:18202122, ECO:0000269PubMed:18614015}. Note=In sperm, secretion gradually increases during capacitation.
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Disease Associations |
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Tissue Specificity |
Detected in testis and sperm (at protein level). Expressed at high levels in heart, liver, kidney, and testis. {ECO:0000269PubMed:18202122}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
8
[view]
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Protein-Protein |
8
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2180167
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InterPro |
IPR004443
YjeF N-terminal domain
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PFAM |
PF03853
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8K4Z3
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PhosphoSite |
PhosphoSite-Q8K4Z3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
246703
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UniGene |
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RefSeq |
NP_659146
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MGI ID |
3ROZ
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MGI Symbol |
Apoa1bp
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OMIM |
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CCDS |
CCDS17464
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HPRD |
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IMGT |
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EMBL |
AJ344092
AK159846
AY566271
BC058362
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GenPept |
AAH58362
AAT70236
BAE35424
CAC86966
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