Mus musculus Protein: Slc18a1
Summary
InnateDB Protein IDBP-159701.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc18a1
Protein Name solute carrier family 18 (vesicular monoamine), member 1
Synonyms 4832416I10Rik; Vat1; Vmat1;
Species Mus musculus
Ensembl Protein ENSMUSP00000046924
InnateDB Gene IDBG-159699 (Slc18a1)
Protein Structure
UniProt Annotation
Function Involved in the transport of biogenic monoamines, such as serotonin, from the cytoplasm into the secretory vesicles of neuroendocrine and endocrine cells. {ECO:0000250}.
Subcellular Localization Cytoplasmic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015238 drug transmembrane transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0006836 neurotransmitter transport
GO:0006855 drug transmembrane transport
GO:0015893 drug transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
GO:0030659 cytoplasmic vesicle membrane
Protein Structure and Domains
PDB ID MGI:106684
InterPro IPR004734 Multidrug resistance protein
IPR005828 General substrate transporter
IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR020846 Major facilitator superfamily domain
PFAM PF00083
PF07690
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R090
PhosphoSite PhosphoSite-Q8R090
TrEMBL Q32XG7
UniProt Splice Variant
Entrez Gene 110877
UniGene Mm.19301
RefSeq NP_694694
MGI ID
MGI Symbol Slc18a1
OMIM
CCDS CCDS22344
HPRD
IMGT
EMBL AY779336 BC027192 BC031146 CH466569
GenPept AAH27192 AAH31146 AAX19142 EDL28728