InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mfng

Summary

InnateDB Protein

IDBP-159755.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mfng

Protein Name

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Synonyms

AW546563;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000018313

InnateDB Gene

IDBG-159753 (Mfng)

Protein Structure

UniProt Annotation

Function

Glycosyltransferase involved in the elongation of O- linked ligands to activate Notch signaling. Possesses fucose- specific beta-1,3-N-acetylglucosaminyltransferase activity.

Subcellular Localization

Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0016757	transferase activity, transferring glycosyl groups
GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
GO:0046872	metal ion binding

Biological Process

GO:0007389	pattern specification process
GO:0008152	metabolic process
GO:0032092	positive regulation of protein binding
GO:0045747	positive regulation of Notch signaling pathway