Version 5.4
Mus musculus Protein: Pomt2
Summary
InnateDB Protein IDBP-159816.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pomt2
Protein Name protein-O-mannosyltransferase 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000035260
InnateDB Gene IDBG-159814 (Pomt2)
Protein Structure
UniProt Annotation
Function Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Ubiquitous. Highly expressed in the acrosome of cap phase spermatids, in spermatocytes and liver. Isoform 1 seems to be testis-specific. {ECO:0000269PubMed:12460945}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000030 mannosyltransferase activity
GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006493 protein O-linked glycosylation
GO:0035269 protein O-linked mannosylation
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2444430
InterPro IPR003342 Glycosyl transferase, family 39
IPR016093 MIR motif
PFAM PF02366
PF02815
PRINTS
PIRSF
SMART SM00472
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BGQ4
PhosphoSite PhosphoSite-Q8BGQ4
TrEMBL
UniProt Splice Variant
Entrez Gene 217734
UniGene Mm.401963
RefSeq NP_700464
MGI ID
MGI Symbol Pomt2
OMIM
CCDS CCDS26070
HPRD
IMGT
EMBL AF246235 AK050915 AY028993 AY090481 AY090482 AY090483 BC052045
GenPept AAH52045 AAK30026 AAL85627 AAM09080 AAM09081 AAM12047 AAM12048 BAC34458

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca