InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mia1

Summary

InnateDB Protein

IDBP-160043.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mia1

Protein Name

melanoma inhibitory activity 1

Synonyms

CD-RAP; Cdrap; Mia1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000071876

InnateDB Gene

IDBG-486365 (Mia1)

Protein Structure

UniProt Annotation

Function

Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas. {ECO:0000250}.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

All malignant melanoma cell lines tested and infrequently in glioma cell lines.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008083	growth factor activity

Biological Process

GO:0007160	cell-matrix adhesion
GO:0030198	extracellular matrix organization

Cellular Component

GO:0005576

extracellular region

Protein Structure and Domains

PDB ID

MGI:109615

InterPro

IPR001452 SH3 domain
IPR011511 Variant SH3 domain

PFAM

PF00018
PF14604
PF07653

PRINTS

PR00452

PIRSF

SMART

SM00326

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q61865

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

12587

UniGene

Mm.262447

RefSeq

NP_062267

MGI ID

MGI Symbol

Mia

OMIM

CCDS

CCDS21013

HPRD

IMGT

EMBL

U85612 X94322 X97965

GenPept

AAB42082 CAA63983 CAA66608