Version 5.4
Mus musculus Protein: Cox17
Summary
InnateDB Protein IDBP-160129.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cox17
Protein Name cytochrome c oxidase, subunit XVII assembly protein homolog (yeast)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000054086
InnateDB Gene IDBG-160127 (Cox17)
Protein Structure
UniProt Annotation
Function Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion intermembrane space {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005507 copper ion binding
GO:0016531 copper chaperone activity
Biological Process
GO:0006825 copper ion transport
Cellular Component
GO:0005758 mitochondrial intermembrane space
Protein Structure and Domains
PDB ID MGI:1333806
InterPro IPR007745 Cytochrome c oxidase copper chaperone
IPR009069 Cysteine alpha-hairpin motif superfamily
PFAM PF05051
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P56394
PhosphoSite PhosphoSite-P56394
TrEMBL Q54AC6
UniProt Splice Variant
Entrez Gene 12856
UniGene
RefSeq NP_001017429
MGI ID
MGI Symbol Cox17
OMIM
CCDS CCDS28165
HPRD
IMGT
EMBL AA168035 AB047323 AK148493 AK152968 AK158051 BC048668 CH466521
GenPept AAH48668 BAB32486 BAE28585 BAE31628 BAE34337 EDK97974

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca