InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Bnc2

Summary

InnateDB Protein

IDBP-160402.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bnc2

Protein Name

basonuclin 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000099884

InnateDB Gene

IDBG-160398 (Bnc2)

Protein Structure

UniProt Annotation

Function

Probable transcription factor specific for skin keratinocytes. May play a role in the differentiation of spermatozoa and oocytes.

Subcellular Localization

Nucleus {ECO:0000269PubMed:15081112}.

Disease Associations

Tissue Specificity

Highly expressed in ovary, testis and kidney. Expressed at moderate levels in skin and small intestine, and at lower levels in lung. Trace amounts of expression detected in liver and colon. Not detected in brain, spleen or thymus. {ECO:0000269PubMed:14988505, ECO:0000269PubMed:15081112}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0003416	endochondral bone growth
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0043586	tongue development
GO:0060021	palate development
GO:0060485	mesenchyme development