InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gpr1

Summary

InnateDB Protein

IDBP-160497.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gpr1

Protein Name

G protein-coupled receptor 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000051417

InnateDB Gene

IDBG-160495 (Gpr1)

Protein Structure

UniProt Annotation

Function

Receptor for the inflammation-associated leukocyte chemoattractant chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation. Can act as a coreceptor for HIV-1 (By similarity). {ECO:0000250}.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0004930	G-protein coupled receptor activity

Biological Process

GO:0007186

G-protein coupled receptor signaling pathway

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2385324

InterPro

IPR000248 Angiotensin II receptor family
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR002275 G protein-coupled receptor 1 orphan
IPR017452 GPCR, rhodopsin-like, 7TM

PFAM

PF00001

PRINTS

PR00241
PR00237
PR01146

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8K087