Version 5.4
Mus musculus Protein: Oxa1l
Summary
InnateDB Protein IDBP-160971.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Oxa1l
Protein Name oxidase assembly 1-like
Synonyms 1810020M02Rik; AI894287;
Species Mus musculus
Ensembl Protein ENSMUSP00000000985
InnateDB Gene IDBG-160969 (Oxa1l)
Protein Structure
UniProt Annotation
Function Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome oxidase. Required for the correct biogenesis of ATP synthase and complex I in mitochondria (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0042803 protein homodimerization activity
GO:0097177 mitochondrial ribosome binding
Biological Process
GO:0051205 protein insertion into membrane
GO:0051262 protein tetramerization
GO:0097031 mitochondrial respiratory chain complex I biogenesis
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
Protein Structure and Domains
PDB ID MGI:1916339
InterPro IPR001708 Membrane insertase OXA1/ALB3/YidC
IPR028055 Membrane insertase YidC/Oxa1, C-terminal
PFAM PF02096
PRINTS PR00701
PR01900
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BGA9
PhosphoSite PhosphoSite-Q8BGA9
TrEMBL
UniProt Splice Variant
Entrez Gene 69089
UniGene Mm.182340
RefSeq NP_081212
MGI ID
MGI Symbol Oxa1l
OMIM
CCDS CCDS27086
HPRD
IMGT
EMBL AK007567 AK044817 AK052432 AK077624 BC027191
GenPept AAH27191 BAB25113 BAC32104 BAC34985 BAC36908

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca