Mus musculus Protein: Tssk6
Summary
InnateDB Protein IDBP-161050.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tssk6
Protein Name testis-specific serine kinase 6
Synonyms Sstk;
Species Mus musculus
Ensembl Protein ENSMUSP00000062783
InnateDB Gene IDBG-161048 (Tssk6)
Protein Structure
UniProt Annotation
Function Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling. {ECO:0000269PubMed:15870294}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in the testis, localized to the heads of elongating spermatids. {ECO:0000269PubMed:15870294}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0006468 protein phosphorylation
GO:0007275 multicellular organismal development
GO:0009103 lipopolysaccharide biosynthetic process
GO:0035092 sperm chromatin condensation
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:2148775
InterPro IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR010440 Lipopolysaccharide kinase
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain
PFAM PF00069
PF07714
PF06293
PRINTS PR00109
PIRSF
SMART SM00220
SM00219
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q925K9
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 83984
UniGene Mm.432504
RefSeq NP_114393
MGI ID
MGI Symbol Tssk6
OMIM
CCDS CCDS22354
HPRD
IMGT
EMBL AF329484 AK076653 BC049542
GenPept AAK48828 BAC36437