Version 5.4
Mus musculus Protein: Mau2
Summary
InnateDB Protein IDBP-161151.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mau2
Protein Name MAU2 chromatid cohesion factor homolog (C. elegans)
Synonyms 9130404D08Rik; A930019L04Rik; C77863; C79014; Mau-2; mKIAA0892;
Species Mus musculus
Ensembl Protein ENSMUSP00000054763
InnateDB Gene IDBG-161147 (Mau2)
Protein Structure
UniProt Annotation
Function Required for association of the cohesin complex with chromatin during interphase. Plays a role in sister chromatid cohesion and normal progression through prometaphase (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nucleoplasm {ECO:0000250}. Note=Binds to chromatin from the end of mitosis until prophase. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0047485 protein N-terminus binding
Biological Process
GO:0034088 maintenance of mitotic sister chromatid cohesion
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0032116 SMC loading complex
Protein Structure and Domains
PDB ID MGI:1921799
InterPro IPR019440 Cohesin loading factor
IPR019734 Tetratricopeptide repeat
PFAM PF10345
PF13174
PF13176
PF13181
PRINTS
PIRSF
SMART SM00028
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D2X5
PhosphoSite PhosphoSite-Q9D2X5
TrEMBL
UniProt Splice Variant
Entrez Gene 74549
UniGene Mm.269061
RefSeq NP_083269
MGI ID
MGI Symbol Mau2
OMIM
CCDS CCDS40364
HPRD
IMGT
EMBL AK018662 AK049277 AK081967 AK220358 BC023401 BC125568 BC132139 BC144990
GenPept AAH23401 AAI25569 AAI32140 AAI44991 BAB31331 BAC33653 BAC38382 BAD90246

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca