InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lrp10

Summary

InnateDB Protein

IDBP-161279.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lrp10

Protein Name

low-density lipoprotein receptor-related protein 10

Synonyms

Lrp9;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000022782

InnateDB Gene

IDBG-161277 (Lrp10)

Protein Structure

UniProt Annotation

Function

Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver. {ECO:0000269PubMed:11123907}.

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Membrane, coated pit {ECO:0000250}.

Disease Associations

Tissue Specificity

Highly expressed in heart, lung, liver and liver. Expressed at low level in brain and spleen. Weakly or not expressed in testis and skeletal muscle. In liver, it is expressed in hepatocytes and at higher level in sinusoidal lining. In the kidney, it is expressed in peritubular capillaries. In brain, it is expressed in the epithelium of the choroid plexus ependymal cells of the third ventricle pia matter, and to lesser extent in hippocampal fields CA2 and CA3. {ECO:0000269PubMed:11123907}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.