Version 5.4
Mus musculus Protein: Slc35d2
Summary
InnateDB Protein IDBP-161502.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc35d2
Protein Name solute carrier family 35, member D2
Synonyms 5730408I21Rik; hfrc; mUGTrel8; SQV7L; UGTrel8;
Species Mus musculus
Ensembl Protein ENSMUSP00000097040
InnateDB Gene IDBG-161496 (Slc35d2)
Protein Structure
UniProt Annotation
Function Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling (By similarity). {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0008643 carbohydrate transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1917734
InterPro IPR004853 Triose-phosphate transporter domain
PFAM PF03151
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q762D5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 70484
UniGene Mm.390044
RefSeq NP_001001321
MGI ID
MGI Symbol Slc35d2
OMIM
CCDS CCDS26595
HPRD
IMGT
EMBL AB117931 AB117932 AK154257 AK159148 BC046402 BC107211
GenPept AAH46402 AAI07212 BAD18884 BAD18885 BAE32469 BAE34855

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca