InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Atp6v1b1

Summary

InnateDB Protein

IDBP-161608.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Atp6v1b1

Protein Name

ATPase, H+ transporting, lysosomal V1 subunit B1

Synonyms

Atp6b1; AW208839; D630003L15; D630030L16Rik; D630039P21Rik; Vpp-3; Vpp3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000006431

InnateDB Gene

IDBG-161606 (Atp6v1b1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 73 interaction(s) predicted by orthology.

Predicted by orthology
Total	73 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding
GO:0015078	hydrogen ion transmembrane transporter activity
GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
GO:0032403	protein complex binding

Biological Process

GO:0001503	ossification
GO:0006885	regulation of pH
GO:0007588	excretion
GO:0007605	sensory perception of sound
GO:0015991	ATP hydrolysis coupled proton transport
GO:0015992	proton transport
GO:0042472	inner ear morphogenesis
GO:0045851	pH reduction
GO:0046034	ATP metabolic process
GO:0055074	calcium ion homeostasis

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005902	microvillus
GO:0016020	membrane
GO:0016323	basolateral plasma membrane
GO:0016324	apical plasma membrane
GO:0016328	lateral plasma membrane
GO:0016471	vacuolar proton-transporting V-type ATPase complex
GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain
GO:0033180	proton-transporting V-type ATPase, V1 domain
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:103285

InterPro

IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain
IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal
IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain
IPR005723 ATPase, V1 complex, subunit B
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00006
PF00306
PF02874

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-NP_598918