InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fam129b

Summary

InnateDB Protein

IDBP-161746.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fam129b

Protein Name

family with sequence similarity 129, member B

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000028135

InnateDB Gene

IDBG-161744 (Fam129b)

Protein Structure

UniProt Annotation

Function

May play a role in apoptosis suppression. {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytosol {ECO:0000269PubMed:21148485}. Cell junction, adherens junction {ECO:0000250}. Note=In exponentially growing cells, exclusively cytoplasmic. Cell membrane localization is observed when cells reach confluency and during telophase (By similarity). Phosphorylation may play a role in relocalization to the membrane (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0043066

negative regulation of apoptotic process

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0005912	adherens junction
GO:0015629	actin cytoskeleton
GO:0070062	extracellular vesicular exosome