Version 5.4
Mus musculus Protein: Kdelr3
Summary
InnateDB Protein IDBP-161825.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kdelr3
Protein Name KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
Synonyms AI173274;
Species Mus musculus
Ensembl Protein ENSMUSP00000010974
InnateDB Gene IDBG-161823 (Kdelr3)
Protein Structure
UniProt Annotation
Function Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptor recognizes K-D-E-L (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0046923 ER retention sequence binding
Biological Process
GO:0006621 protein retention in ER lumen
GO:0008150 biological_process
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005575 cellular_component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2145953
InterPro IPR000133 ER lumen protein retaining receptor
PFAM PF00810
PRINTS PR00660
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R1L4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 105785
UniGene Mm.298199
RefSeq NP_598851
MGI ID
MGI Symbol Kdelr3
OMIM
CCDS CCDS27642
HPRD
IMGT
EMBL AK136991 BC011472 BC024420
GenPept AAH11472 AAH24420 BAE23198

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca