InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Boc

Summary

InnateDB Protein

IDBP-162158.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Boc

Protein Name

biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000023370

InnateDB Gene

IDBG-162156 (Boc)

Protein Structure

UniProt Annotation

Function

Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells.

Subcellular Localization

Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Highly expressed in embryonic somites, limb buds, dermomyotomes and in the neural tube. {ECO:0000269PubMed:11782431}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007224	smoothened signaling pathway
GO:0007411	axon guidance
GO:0016202	regulation of striated muscle tissue development
GO:0016337	single organismal cell-cell adhesion
GO:0030030	cell projection organization
GO:0045663	positive regulation of myoblast differentiation

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0009986	cell surface
GO:0030424	axon
GO:0030426	growth cone
GO:0043025	neuronal cell body
GO:0044295	axonal growth cone

Protein Structure and Domains

PDB ID

MGI:2151153

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013151 Immunoglobulin

PFAM

PF00041
PF01108
PF07679
PF00047

PRINTS

PIRSF

SMART

SM00408
SM00409
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q6AZB0