Version 5.4
Homo sapiens Protein: TSR1
Summary
InnateDB Protein IDBP-16239.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSR1
Protein Name TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000301364
InnateDB Gene IDBG-16237 (TSR1)
Protein Structure
UniProt Annotation
Function Required during maturation of the 40S ribosomal subunit in the nucleolus. {ECO:0000250}.
Subcellular Localization Nucleus, nucleolus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 84 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 84 [view]
Protein-Protein 84 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0044822 poly(A) RNA binding
Biological Process
GO:0042254 ribosome biogenesis
GO:0042255 ribosome assembly
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID
InterPro IPR007034 Ribosome biogenesis protein BMS1/TSR1, C-terminal
IPR009000 Translation protein, beta-barrel domain
IPR012948 AARP2CN
PFAM PF04950
PF08142
PRINTS
PIRSF
SMART SM00785
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2NL82
PhosphoSite PhosphoSite-Q2NL82
TrEMBL
UniProt Splice Variant
Entrez Gene 55720
UniGene Hs.388170
RefSeq NP_060598
HUGO HGNC:25542
OMIM 611214
CCDS CCDS32525
HPRD 07681
IMGT
EMBL AB037822 AK001396 BC019090 BC110851 BC126110 CH471108
GenPept AAH19090 AAI10852 AAI26111 BAA91667 BAA92639 EAW90552

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca