Mus musculus Protein: Ralgps1
Summary
InnateDB Protein IDBP-162421.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ralgps1
Protein Name Ral GEF with PH domain and SH3 binding motif 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000048451
InnateDB Gene IDBG-162419 (Ralgps1)
Protein Structure
UniProt Annotation
Function Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeleton organization. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Associates with membranes through the PH domain. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0008321 Ral guanyl-nucleotide exchange factor activity
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0032315 regulation of Ral GTPase activity
Cellular Component
GO:0005575 cellular_component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:1922008
InterPro IPR001849 Pleckstrin homology domain
IPR001895 Guanine-nucleotide dissociation stimulator CDC25
IPR023578 Ras guanine nucleotide exchange factor, domain
PFAM PF00169
PF00617
PRINTS
PIRSF
SMART SM00233
SM00147
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2AR50
PhosphoSite PhosphoSite-A2AR50
TrEMBL
UniProt Splice Variant
Entrez Gene 241308
UniGene Mm.473240
RefSeq NP_001277501
MGI ID 2DTC
MGI Symbol Ralgps1
OMIM
CCDS CCDS71031
HPRD
IMGT
EMBL AK017939 AK076767 AK129123 AL845277 AL929197 BC072656
GenPept AAH72656 BAC25535 BAC36473 BAC97933 CAM22214 CAM22215 CAM22216 CAM22217 CAM25544 CAM25545 CAM25546