InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cndp2

Summary

InnateDB Protein

IDBP-162506.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cndp2

Protein Name

CNDP dipeptidase 2 (metallopeptidase M20 family)

Synonyms

0610010E05Rik; C76600; Cn2; Dip-2; Pep-1; Pep1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025546

InnateDB Gene

IDBG-162504 (Cndp2)

Protein Structure

UniProt Annotation

Function

Hydrolyzes a variety of dipeptides including L- carnosine. Has a strong preference for Cys-Gly (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Highly expressed in the parafascicular nucleus of the thalamus, tuberomammillary nucleus of the hypothalamus and the mitral cell layer of the olfactory bulb. {ECO:0000269PubMed:15749831}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004180	carboxypeptidase activity
GO:0008233	peptidase activity
GO:0008237	metallopeptidase activity
GO:0016787	hydrolase activity
GO:0016805	dipeptidase activity
GO:0034701	tripeptidase activity
GO:0046872	metal ion binding