Version 5.4
Mus musculus Protein: Il25
Summary
InnateDB Protein IDBP-162542.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Il25
Protein Name interleukin 25
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000039641
InnateDB Gene IDBG-162540 (Il25)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0030380 interleukin-17E receptor binding
Biological Process
GO:0002437 inflammatory response to antigenic stimulus
GO:0006954 inflammatory response
GO:0009620 response to fungus
GO:0009624 response to nematode
GO:0030222 eosinophil differentiation
GO:0045087 innate immune response (InnateDB)
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:2155888
InterPro IPR010345 Interleukin-17 family
IPR029034 Cystine-knot cytokine
PFAM PF06083
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8VHH8
UniProt Splice Variant
Entrez Gene 140806
UniGene Mm.90154
RefSeq NP_542767
MGI ID
MGI Symbol Il25
OMIM
CCDS CCDS36926
HPRD
IMGT
EMBL AF458060 BC120568 BC125524 BC144962 CT025533
GenPept AAI20569 AAI25525 AAI44963 AAL57623

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca