Version 5.4
Mus musculus Protein: Angptl2
Summary
InnateDB Protein IDBP-162569.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Angptl2
Protein Name angiopoietin-like 2
Synonyms AI593246; Arp2; AW260363;
Species Mus musculus
Ensembl Protein ENSMUSP00000004208
InnateDB Gene IDBG-162567 (Angptl2)
Protein Structure
UniProt Annotation
Function Induces sprouting in endothelial cells through an autocrine and paracrine action. {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity Widely expressed in heart, tongue, lung and skeletal muscle. Also found in lower levels in kidney, epididymis and testis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005576 extracellular region
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1347002
InterPro IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
IPR010989 t-SNARE
PFAM PF00147
PRINTS
PIRSF
SMART SM00186
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9R045
PhosphoSite PhosphoSite-Q9R045
TrEMBL
UniProt Splice Variant
Entrez Gene 26360
UniGene Mm.208919
RefSeq NP_036053
MGI ID
MGI Symbol Angptl2
OMIM
CCDS CCDS15940
HPRD
IMGT
EMBL AF125176 AK037265 AK155464 AL845277 BC138609 BC138610 CH466542
GenPept AAD55358 AAI38610 AAI38611 BAC29780 BAE33276 CAM22212 EDL08597

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca