Version 5.4
Mus musculus Protein: Lcorl
Summary
InnateDB Protein IDBP-162668.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lcorl
Protein Name ligand dependent nuclear receptor corepressor-like
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000042677
InnateDB Gene IDBG-162666 (Lcorl)
Protein Structure
UniProt Annotation
Function May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3'. May play a role in spermatogenesis. {ECO:0000269PubMed:12560079}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00320}.
Disease Associations
Tissue Specificity Expressed predominantly in the spermatocytes of the testis. Also found in the kidney, liver and heart. {ECO:0000269PubMed:12560079}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:2651932
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3U285
PhosphoSite PhosphoSite-Q3U285
TrEMBL E9PXY2
UniProt Splice Variant
Entrez Gene 209707
UniGene Mm.71498
RefSeq NP_835278
MGI ID
MGI Symbol Lcorl
OMIM
CCDS CCDS19277
HPRD
IMGT
EMBL AB076078 AC093341 AC158786 AK041987 AK043498 AK043845 AK083689 AK154398 AK155421 BC066151 BC138563
GenPept AAH66151 AAI38564 BAC20954 BAC31123 BAC31560 BAC31678 BAC38994 BAE32559 BAE33257

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca