Version 5.4
Mus musculus Protein: Upb1
Summary
InnateDB Protein IDBP-162712.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Upb1
Protein Name ureidopropionase, beta
Synonyms AI195023;
Species Mus musculus
Ensembl Protein ENSMUSP00000049342
InnateDB Gene IDBG-162710 (Upb1)
Protein Structure
UniProt Annotation
Function Converts N-carbamyl-beta-aminoisobutyric acid and N- carbamyl-beta-alanine to, respectively, beta-aminoisobutyric acid and beta-alanine, ammonia and carbon dioxide.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003837 beta-ureidopropionase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0046872 metal ion binding
Biological Process
GO:0006807 nitrogen compound metabolic process
GO:0019483 beta-alanine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:2143535
InterPro IPR003010 Carbon-nitrogen hydrolase
PFAM PF00795
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VC97
PhosphoSite PhosphoSite-Q8VC97
TrEMBL Q3UEK4
UniProt Splice Variant
Entrez Gene 103149
UniGene Mm.441195
RefSeq NP_598756
MGI ID
MGI Symbol Upb1
OMIM
CCDS CCDS23925
HPRD
IMGT
EMBL AK149373 AK149480 BC021388 BC024447 CH466553
GenPept AAH21388 AAH24447 BAE28841 BAE28907 EDL31923

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca