InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dnalc4

Summary

InnateDB Protein

IDBP-162718.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dnalc4

Protein Name

dynein, axonemal, light chain 4

Synonyms

D15Ertd424e; Dnalc4;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000023055

InnateDB Gene

IDBG-162716 (Dnalc4)

Protein Structure

UniProt Annotation

Function

Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003774	motor activity

Biological Process

GO:0007017	microtubule-based process
GO:0008152	metabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0005874	microtubule
GO:0005875	microtubule associated complex
GO:0005929	cilium
GO:0030286	dynein complex

Protein Structure and Domains

PDB ID

MGI:1859217

InterPro

IPR001372 Dynein light chain, type 1/2

PFAM

PF01221

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9DCM4

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

54152

UniGene

Mm.449429

RefSeq

NP_059498

MGI ID

MGI Symbol

Dnal4

OMIM

CCDS

CCDS27650

HPRD

IMGT

EMBL

AB010031 AK002657 AK132061 BC005426

GenPept

AAH05426 BAA24153 BAE20966