InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tmprss5

Summary

InnateDB Protein

IDBP-162723.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tmprss5

Protein Name

transmembrane protease, serine 5 (spinesin)

Synonyms

spinesin;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000064527

InnateDB Gene

IDBG-162721 (Tmprss5)

Protein Structure

UniProt Annotation

Function

May play a role in hearing. {ECO:0000250}.

Subcellular Localization

Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0005044	scavenger receptor activity
GO:0008233	peptidase activity

Biological Process

GO:0006508	proteolysis
GO:0006898	receptor-mediated endocytosis

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043025	neuronal cell body

Protein Structure and Domains

PDB ID

MGI:1933407

InterPro

IPR001190 SRCR domain
IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR017448 SRCR-like domain

PFAM

PF00530
PF00089

PRINTS

PR00258
PR00722

PIRSF

SMART

SM00020
SM00202

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt