Homo sapiens Protein: GABRG1 | |||||||||||||
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Summary | |||||||||||||
InnateDB Protein | IDBP-16286.5 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | GABRG1 | ||||||||||||
Protein Name | gamma-aminobutyric acid (GABA) A receptor, gamma 1 | ||||||||||||
Synonyms | |||||||||||||
Species | Homo sapiens | ||||||||||||
Ensembl Protein | ENSP00000295452 | ||||||||||||
InnateDB Gene | IDBG-16282 (GABRG1) | ||||||||||||
Protein Structure | |||||||||||||
UniProt Annotation | |||||||||||||
Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. | ||||||||||||
Subcellular Localization | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. | ||||||||||||
Disease Associations | |||||||||||||
Tissue Specificity | |||||||||||||
Comments | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||
PDB ID | |||||||||||||
InterPro |
IPR001390
Gamma-aminobutyric-acid A receptor, alpha subunit IPR005437 Gamma-aminobutyric-acid A receptor, gamma subunit IPR005438 Gamma-aminobutyric-acid A receptor, gamma 1 subunit IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alpha IPR006029 Neurotransmitter-gated ion-channel transmembrane domain IPR006201 Neurotransmitter-gated ion-channel IPR006202 Neurotransmitter-gated ion-channel ligand-binding |
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PFAM |
PF02932
PF02931 |
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PRINTS |
PR01079
PR01620 PR01621 PR00253 PR00252 |
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PIRSF | |||||||||||||
SMART | |||||||||||||
TIGRFAMs | |||||||||||||
Post-translational Modifications | |||||||||||||
Modification | |||||||||||||
Cross-References | |||||||||||||
SwissProt | Q8N1C3 | ||||||||||||
PhosphoSite | PhosphoSite-Q8N1C3 | ||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 2565 | ||||||||||||
UniGene | Hs.375051 | ||||||||||||
RefSeq | NP_775807 | ||||||||||||
HUGO | HGNC:4086 | ||||||||||||
OMIM | 137166 | ||||||||||||
CCDS | CCDS3470 | ||||||||||||
HPRD | 15923 | ||||||||||||
IMGT | |||||||||||||
EMBL | AK122845 BC031087 CH471069 CR933628 | ||||||||||||
GenPept | AAH31087 BAG53758 CAI45936 EAW93021 | ||||||||||||