Mus musculus Protein: Dmrta1
Summary
InnateDB Protein IDBP-162982.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dmrta1
Protein Name doublesex and mab-3 related transcription factor like family A1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000057488
InnateDB Gene IDBG-162980 (Dmrta1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00070}.
Disease Associations
Tissue Specificity Widely expressed, with highest levels in ovary, testis, epididymis, preputial gland, vomeronasal organ, liver, salivary glands and heart. Also expressed throughout the brain with highest levels in the olfactory bulbs and medulla. Detected at similar levels in gonads of both sexes. {ECO:0000269PubMed:12609607, ECO:0000269PubMed:16982677}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0001541 ovarian follicle development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0060179 male mating behavior
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:2653627
InterPro IPR001275 DM DNA-binding domain
IPR005173 DMRTA motif
IPR009060 UBA-like
PFAM PF00751
PF03474
PRINTS
PIRSF
SMART SM00301
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CFG4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 242523
UniGene Mm.130167
RefSeq NP_783578
MGI ID
MGI Symbol Dmrta1
OMIM
CCDS CCDS18352
HPRD
IMGT
EMBL AF542047 AL772403
GenPept AAN77234 CAM24936