InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SGTA

Summary

InnateDB Protein

IDBP-16309.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SGTA

Protein Name

small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha

Synonyms

alphaSGT; hSGT; SGT;

Species

Homo sapiens

Ensembl Protein

ENSP00000221566

InnateDB Gene

IDBG-16307 (SGTA)

Protein Structure

UniProt Annotation

Function

Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. {ECO:0000269PubMed:18759457}.

Subcellular Localization

Disease Associations

Tissue Specificity

Ubiquitous.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 103 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	103 [view]
Protein-Protein	102 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0008150	biological_process
GO:0016032	viral process

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001440 Tetratricopeptide TPR1
IPR013026 Tetratricopeptide repeat-containing domain
IPR013105 Tetratricopeptide TPR2
IPR019734 Tetratricopeptide repeat

PFAM

PF00515
PF07719
PF13174
PF13176
PF13181

PRINTS

PIRSF

SMART

SM00028

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O43765