InnateDB Protein
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IDBP-163139.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Emx1
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Protein Name
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empty spiracles homolog 1 (Drosophila)
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000046026
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InnateDB Gene
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IDBG-163137 (Emx1)
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Protein Structure
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Function |
Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system. {ECO:0000269PubMed:1353865, ECO:0000269PubMed:15147765}.
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Subcellular Localization |
Nucleus {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Cerebral cortex. Expressed in the olfactory bulbs. {ECO:0000269PubMed:1353865, ECO:0000269PubMed:20887964}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated |
Total |
16
[view]
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Protein-Protein |
16
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
7 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:95387
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InterPro |
IPR001356
Homeobox domain
IPR009057
Homeodomain-like
IPR020479
Homeodomain, metazoa
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PFAM |
PF00046
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PRINTS |
PR00024
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PIRSF |
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SMART |
SM00389
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TIGRFAMs |
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Modification |
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SwissProt |
Q04742
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
13796
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UniGene |
Mm.391473
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RefSeq |
NP_034261
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MGI ID |
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MGI Symbol |
Emx1
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OMIM |
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CCDS |
CCDS20290
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HPRD |
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IMGT |
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EMBL |
BC104322
BC104323
X68881
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GenPept |
CAA48752
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