InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sfxn5

Summary

InnateDB Protein

IDBP-163177.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sfxn5

Protein Name

sideroflexin 5

Synonyms

C230001H08Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000041872

InnateDB Gene

IDBG-163175 (Sfxn5)

Protein Structure

UniProt Annotation

Function

Transports citrate. Potential iron transporter (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed in liver and brain. {ECO:0000269PubMed:11274051}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008324	cation transmembrane transporter activity
GO:0015137	citrate transmembrane transporter activity

Biological Process

GO:0006812	cation transport
GO:0015746	citrate transport
GO:0055072	iron ion homeostasis
GO:0055085	transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2137681

InterPro

IPR004686 Tricarboxylate/iron carrier

PFAM

PF03820

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q925N0

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

94282

UniGene

Mm.418424

RefSeq

NP_848754

MGI ID

MGI Symbol

Sfxn5

OMIM

CCDS

CCDS20291

HPRD

IMGT

EMBL

AF325264 AK036285 AK082073

GenPept

AAK39432 BAC29372 BAC38403